There is a long spotted history relating the effect
of viral infections and essential fatty acid metabolism. In 1935, soon after
the discovery of EFA's, it was published that viral infections were associated
with an abrupt fall in the iodine value of the blood which indicated a fall
in the plasma concentration of EFA's.
It wasn't until some 40 years later
that Stoesser and his group found that infection of human cell lines with
certain viruses could interfere with the ability of those cells to desaturate
linoleic acid. More recently, it was found that Epstein-Barr virus infection
in young adults (mono) is associated with prolonged falls in the plasma
levels of both Linoleic Acid and its metabolites (GLA, DGLA, AA).
Finally,
the now deceased eminent scientist Dr. David Horrobin (my
mentor) brought
these research results to clinical practice with Dr. Peter Behan in a randomized
double blind placebo-controlled study of "Essential Fatty Acids in the Treatment
of Postviral Fatigue Syndrome" published in 1990. What does this have
to do with the H1N1 Flu---well just about everything if you understand EFA
metabolism, flu symptoms, and the actions of viral replication at the cellular
level. Observations by Dr. Horrobin raised 2 important effects of EFA's on
viruses.
1) EFA's themselves can disrupt and inactivate those viruses that have a
lipid envelope---the effect is greater the greater the degree of desaturation.
(references available upon request)
2) The action of interferon against viruses
requires the presence of the cyclo-oxygenase enzyme, which suggests that prostaglandin
metabolites of EFA's might be required for the full expression of interferon
action against viruses.
(references available upon request)
If the above is true (research
supports these facts) then this science would also explain why atopic people
are abnormally susceptible to many viral infections and patients with certain
viral infections like EB and AIDS viruses develop full-blown atopic syndromes.
Viruses attempt upon entering the cell due to an EFA deficiency in the
membrane, to inhibit Delta 6 desaturase so the cell cannot make enough EFA
metabolites to deactivate the virus.
In this way our cell becomes the host
of the virus.
Current research
(U.S.
Patent # 4,841,023) applies to the
inactivation of viruses in blood plasma. According to the patent--unsaturated
fatty acids with at least one double bond in the cis configuration (biologically
active) and containing 16-20 carbon atoms are effective in deactivating
viruses that are enveloped. (i.e. FLU viruses). The patent includes a list
of fatty acids, but the most important for the purpose of this paper are:
linoleic, linolenic gamma-linolenic, arachidonic and palmetic fatty acids.
Small concentrations of these fatty acids will deactivate enveloped viruses
like Herpes, influenza etc. within minutes.
(see patent for details)
Research has shown that
long chain saturated fatty acids and short chain saturated fatty acids
have NO anti-viral effect. But, Medium chain saturated and long chain unsaturated
fatty acids deactivate enveloped viruses. The loss of the ability of
the virus to spread and infect is attributed to the disruption of the lipoprotein
envelope of the virus and has been observed many times under electron
microscopes. (references available upon request)
In closing; if you really
want to avoid catching the H1N1 flu and don't want to experiment with your
families health with the "safe" vaccine, then do this; eat
like your great grandfather; get rid of the BAD fats and processed food
and get some Evening Primrose oil, Cod liver oil, Coconut oil, vit D3 and
a good multi-min/vit into you. This is even more critical for people with
compromised immune systems (impaired Delta 6); my advice to "sick" people
is to avoid being vaccinated.
The
following are key REFERENCES for my article:
1) Clinical
Biochemistry of Essential Fatty Acids - David F. Horrobin and Mehar S.
Manku - Omega 6 Essential Fatty Acids- Pathophysiology and Roles in Clinical
Medicine pgs.
21-53 (93 references)
2) Stoesser AV - Effect
of Acute Infection on Iodine Number of Serum Fatty Acids Proc. Soc. Exp. Biol. Med.
1935; 32:1326-7
3) Dunbar LM, Bailey
JM - Enzyme Deletions and Essential Fatty Acid Metabolism in Cultured Cells J.
Biol. Chem. 1975; 250:1152-4
4) Williams LL, Doody
DM, Horrocks La, -
Serum Fatty Acid Proportions Are Altered During the Year Following Acute
Epstein-Barr Virus Infection. Lipids 1988; 23:981-8
5) Sands
J, Auperin D., Snipes W. - Extreme Sensitivity of Enveloped
Viruses, Including Herpes Simplex, To Long Chain Unsaturated
MonoGlycerides and Alcohols Antimicrob. Agents
Chemother. 1979; 15:67-73
6)
Soca A.,Rodrigeuz S., Gancedo AG et al --Inactivation and Inhibition
of African Swine Fever Virus by Monooolein, Monolinolein and Gamma- Linollenyl
Alcohol - Arch. Virol. 1986; 88:285-92
7) Chandrabose
KA, Cuatrecasas P., Pottathil R.,Lang DJ. -Interferon- Resistant
Cell Line Lacks Fatty Acid Cyclo-Oxygenase Activity - Science
1981: 212:329-31
8)
GRB Skinner, SL Randall,MA Billstom A Buchan - Antiviral Actions
of Essential Fatty Acids in Vitro -
Omega 6 Essential Fatty Acids in Omega 6 Essential
Fatty Acids- Pathophysiology and Roles in Clinical Medicine 1990
pg261-73 (
29 references)
Do your Homework
– your health will depend on it!
Let's help everyone get healthy,
Paul Beatty
905-648-6887
email: efapaul@yahoo.ca
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